Women's Health Weekly
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Cancer Screening
MIB-1 and PCNA immunostaining used as diagnostic adjunct to cervical Pap smear
August 25th, 2005
Molecular immunology borstel (MIB)-1 and proliferating cell nuclear antigen (PCNA) immunostaining were used as a diagnostic adjunct to cervical Pap smear. "The present study was done to determine the role of MIB-1 and PCNA proliferative index as a diagnostic adjunct to cervical Pap smear for the identification of ascending grades of cervical intraepithelial neoplasia (CIN) developing into cancer in the human uterine cervix. A total of 49 adequate Pap smears with consensus diagnosis were destained for immunocytochemical staining (MIB-1 and PC10)," scientists in India reported. "Staining was done by streptavidin-biotin method after antigen retrieval....
Source: Women's Health Weekly (2005-08-25)
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