Galectin-1

Galectin-1 induced apoptosis in human breast cancer and trophoblast tumor cells

Published in Women's Health Weekly, August 25th, 2005

Scientists claimed that galectin-1 induced apoptosis in human breast cancer and trophoblast tumor cells.

According to recent research from Germany, "Galectin-1 (gal-1), a member of the mammalian beta-galactoside-binding proteins, preferentially recognizes Gal beta 1-4GlcNAc (LacNAc) sequences of oligosaccharides associated with several cell surface glycoconjugates. As demonstrated histochemically, gal-1 recognizes appropriate glycoepitopes on human breast cancer cells (MCF7) and on human chorionic carcinoma cells (BeWo)."

"Gal-1 is expressed in many malignant and normal tissues. A high level of expression is found in lymphatic organs, which feature...

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Source: Women's Health Weekly (2005-08-25)

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