Women's Health Weekly
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Breast Cancer
Decreased breast cancer survival associated with high TRAIL-R2 expression
September 1st, 2005
High expression of TRAIL-R2, a cell surface receptor that triggers cell death, has been shown to be associated with a decrease in the survival rates of breast cancer patients according to a study published by Yale Cancer Center researchers in Clinical Cancer Research (Clinical Cancer Research 2005;11(14) July 15, 2005). Analyzing 20-year follow-up data from breast cancer patients with an automated quantitative analysis system (AQUA) to review tissue microarray specimens, the researchers identified increased intensity of TRAIL receptor expression. AQUA scores were correlated with clinical and pathologic variables. In addition, TRAIL-R1 and TRAIL-R2...
Source: Women's Health Weekly (2005-09-01)
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