Women's Health Weekly
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Gynecology
Marked p16 expression almost always reflects cervical cancer or dysplasia
September 1st, 2005
Marked p16 expression almost always reflects cervical cancer or dysplasia. According to recent research from South Korea, "for evaluating the diagnostic significance of p16(INK4A) over-expression in the uterine cervical intraepithelial neoplasm and in invasive carcinoma, human papillomavirus (HPV) was detected and genotyped by oligonucleotide microarray in archival tissues of 117 cervical specimens, including 47 invasive squamous cell carcinomas (SCC), 30 cases of cervical intraepithelial neoplasia (CIN), 20 adenocarcinomas, and 20 cases of non-neoplastic cervix." "The expression of p16(INK4A) protein was immunohistochemically studied in these cases...
Source: Women's Health Weekly (2005-09-01)
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