Women's Health Weekly
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Embryogenesis
RNA interference delineates essential components of murine embryo development
September 1st, 2005
RNA interference delineates essential components of murine embryo development. According to a study from Canada, "differential gene regulation integrated in time and space drives developmental programs during embryogenesis. To understand how the program of gastrulation is regulated by Wnt/beta-catenin signaling, we have used genome-wide expression profiling of conditional beta-catenin mutant embryos." "Known Wnt/beta-catenin target genes, known components of other signaling pathways, as well as a number of uncharacterized genes were down-regulated in these mutants. To further narrow down the set of differentially expressed genes, we used whole-mount...
Source: Women's Health Weekly (2005-09-01)
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