Women's Health Weekly
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Cervical Cancer
MIB-1 and PCNA immunostaining used as diagnostic adjunct to cervical pap smear
September 8th, 2005
Molecular immunology borstel (MIB)-1 and proliferating cell nuclear antigen (PCNA) immunostaining were used as diagnostic tools for cervical cancer. According to recent research from India, "The present study was done to determine the role of MIB-1 and PCNA proliferative index as a diagnostic adjunct to cervical Papanicolaou (Pap) smear for the identification of ascending grades of cervical intraepithelial neoplasia (CIN) developing into cancer in the human uterine cervix. A total of 49 adequate Pap smears with consensus diagnosis were destained for immunocytochemical staining (MIB-1 and PC10)." "Staining was done by streptavidin-biotin method after...
Source: Women's Health Weekly (2005-09-08)
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