Women's Health Weekly
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Cervical Cancer
MT1-MMP expression associated with cervical cancer
September 8th, 2005
Membrane type 1 matrix metalloproteinase expression (MT1-MMP) has been associated with cervical cancer. According to a study from the United States, "MT1-MMP is frequently expressed by cancer cells and is believed to play an important role in cancer cell invasion and metastasis. However, little is known about the role of MT1-MMP in mediating invasiveness of cervical cancer cells." "In this study, we examined MT1-MMP expression in 58 primary human cervical tissue specimens, including normal cervix, low-grade squamous intraepithelial lesions (LSIL), high-grade SILs (HSIL), and invasive carcinomas. We also evaluated MT1-MMP, MMP-2, and tissue inhibitor...
Source: Women's Health Weekly (2005-09-08)
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