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Cervical Carcinoma

Differing regimens of neoadjuvant chemotherapy compared

According to a study from Italy, "Neoadjuvant chemotherapy may represent an alternative to irradiation in locally advanced squamous cell cervical cancer. Aims of this study were to compare a three-drug (paclitaxel, ifosfamide, and cisplatin [TIP]) with a two-drug (ifosfamide and cisplatin [IP]) regimen and to assess the prognostic value of pathologic response on survival."

"Patients (n=219) were randomly assigned to ifosfamide 5 g/m² during 24 hours plus cisplatin 75 mg/m², or paclitaxel 175 mg/m² plus ifosfamide 5 g/m² during 24 hours and...

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