Women's Health Weekly
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Women's Health Weekly
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Breast Cancer
Recent findings illuminate research in breast cancer
September 15th, 2005
Investigators in the United States, Japan and France have published new breast cancer data. Study 1: Scientists claimed that kinase-inactive glycogen synthase kinase 3 beta (GSK3 beta) promoted Wnt signaling and mammary tumorigenesis. "Recent studies have implicated ectopic activation of the Wnt pathway in many human cancers, including breast cancer. Beta-catenin is a critical coactivator in this signaling pathway and is regulated in a complex fashion by phosphorylation, degradation, and nuclear translocation. GSK3 beta phosphorylation of the NH2-terminal domain of beta-catenin targets it for ubiquitination and proteosomal degradation," researchers...
Source: Women's Health Weekly (2005-09-15)
|
