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Women's Health Weekly

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Breast Cancer



Choline and phosphatidylcholine fluorescent derivatives localization studied



September 15th, 2005

Choline and phosphatidylcholine fluorescent derivatives localization in carcinoma cells were studied by laser scanning confocal fluorescence microscopy.

According to recent research published in the European Journal of Cancer, "In this study, we have shown the intracellular distribution of choline and phosphatidylcholine fluorescent derivatives in human breast carcinoma cells using confocal microscopy. The fluorescent choline derivatives ethanamimium 2-hydroxy-N,N-dimethyl-N-[2-N-(2,1,3-benzoxadiazol-4-amine,-N-methyl,-7-nitro)-ethyl] bromide (NBD-choline) and C(6)-NBD-phosphatidylcholine (C(6)-NBD-PC) were used in this work."

"NBD-choline was...


Source: Women's Health Weekly (2005-09-15)

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