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Women's Health Weekly

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Breast Cancer



Effect of BRCA1/2 test results on perception of risk for familial breast cancer



September 15th, 2005

What effect is there of uninformative BRCA1/2 test results on the perception of risk for familial breast cancer'

Scientists in The Netherlands conducted a study "To test the 'false-reassurance hypothesis,' which suggests that women who receive an uninformative BRCA1/2 test result may incorrectly conclude that they no longer have an elevated risk, with possible harmful consequences for adherence to breast surveillance guidelines. A prospective questionnaire design was used to compare 183 women with an uninformative BRCA test result (94 affected and 89 unaffected) with 41 proven BRCA mutation-carriers and 49 true negatives before and after BRCA1/2 test disclosure."

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Source: Women's Health Weekly (2005-09-15)

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