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Women's Health Weekly

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Cervical Cancer



Fas gene promoter -670 polymorphism (A/G) associated with carcinogenesis



September 15th, 2005

Fas gene promoter -670 polymorphism (A/G) was associated with cervical carcinogenesis.

In a recent article published in the journal Gynecologic Oncology, scientists in Japan conducted a study "to investigate the biological significance of single nucleotide polymorphism (SNP) at Fas gene promoter in cervical carcinogenesis."

"SNP at -670 of Fas gene promoter (A/G) together with human papillomavirus (HPV) types were examined in a total of 279 cervical smear samples and 8 human cervical squamous carcinoma cell lines using polymerase chain reaction and restriction fragment length polymorphism (PCR-RFLP) techniques. Forty-nine patients with...


Source: Women's Health Weekly (2005-09-15)

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