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Women's Health Weekly

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Cervical Cancer



Radiation therapy induced micronuclei in cervical cancer



September 15th, 2005

Radiation therapy was seen to induce micronuclei (MN) in cervical cancer.

Scientists in India conducted a study "to evaluate the predictive value of serial changes in MN induction during external radiotherapy (EXRT) in cervical cancer with respect to local response at the end of EXRT and local disease free survival (LDFS). Twenty-five patients of squamous cell cancer of the cervix were treated by 50 Gy of EXRT delivered over 5 weeks followed by intracavitary brachytherapy."

"Serial cytological smears were taken from cervical growth at weekly intervals during the course of EXRT and stained by Giemsa and May-Grunwald stain. MN induction were scored as...


Source: Women's Health Weekly (2005-09-15)

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