Women's Health Weekly
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Breast Cancer
Folate intake examined for role in risk reduction in certain breast cancers
September 22nd, 2005
Folate intake was examined for its role in risk reduction in certain breast cancers. "Folate plays an important role in DNA methylation, and aberrant methylation of the estrogen receptor (ER) gene may be related to the loss of ER gene expression in breast tumors," investigators in the United States report. "Thus, deficient folate status has been hypothesized to be associated primarily with ER gene-negative breast tumors, but data relating folate intake to breast cancer risk according to ER status are sparse." "A prospective cohort analysis" was conducted by S. M. Zhang and colleagues "of folate intake among 88,744 women in the Nurses' Health Study...
Source: Women's Health Weekly (2005-09-22)
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