Women's Health Weekly
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Breast Cancer
Researchers publish new studies and findings in the area of breast cancer
September 22nd, 2005
New findings from the United States and Portugal describe advances in breast cancer. Study 1: Histone deacetylase (HDAC) inhibitors might enhance the apoptosis-inducing potential of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL). "HDAC inhibitors induce differentiation and/or apoptosis in a variety of cell types by activating transcription of target genes. Activation of the death receptor (DR) pathway by TRAIL induces apoptosis preferentially in cancer cells," scientists in the United States reported. "Here, we investigated the intracellular mechanisms by which HDAC inhibitors (suberoylanilide hydroxamic acid,...
Source: Women's Health Weekly (2005-09-22)
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