Women's Health Weekly
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Cholera Vaccine Development
Immune response kinetics after immunization with cholera toxin reported
September 22nd, 2005
Scientists report the kinetics of local and systemic immune responses after vaginal immunization with recombinant cholera toxin B subunit in humans in a recent issue of Clinical and Diagnostic Laboratory Immunology. "Vaginal vaccination seems to be the best strategy for inducing specific immunoglobulin A (IgA) and IgG antibody responses in the female genital tract. The relative efficiencies of one, two, and three vaginal doses of recombinant cholera toxin B subunit (CTB) in generating mucosal and systemic immune responses in healthy women were evaluated, and the kinetics of the immune responses were monitored for responding volunteers for up to 12 months after...
Source: Women's Health Weekly (2005-09-22)
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