Published in Women's Health Weekly, September 29th, 2005
"BRCA1 associated RING domain protein (BARD1) was originally identified due to its interaction with the RING domain of BRCA1. BARD1 is required for S phase progression, contact inhibition and normal nuclear division, as well as for BRCA1 independent, p53 dependent apoptosis," stated researchers in Canada. "To investigate whether alterations in BARD1 are involved in human breast and ovarian cancer, they used single strand conformation polymorphism analysis and sequencing on 35 breast tumors and cancer cell lines and on 21 ovarian tumors."
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