Women's Health Weekly
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Breast Cancer
Markers associated with the invasive character of breast ductal carcinomas
September 29th, 2005
Markers have been associated with the invasive character of breast ductal carcinomas. According to recent research from Japan, "hypoxia-inducible factor 1 alpha (HIF-1 alpha) is a transcription factor that may play an important role in tumor growth and metastasis by its regulation of angiogenesis and lymphangiogenesis to survive cellular hypoxia. Lymphangiogenesis is promoted by vascular endothelial growth factors (VEGF)-C and VEGF-D, but the correlation between the expression of HIF-1 alpha and VEGF-C or VEGF-D in human breast carcinoma is not well elucidated." "This study examined the pathobiological role of these molecules in human breast ductal...
Source: Women's Health Weekly (2005-09-29)
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