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Women's Health Weekly

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Breast Cancer



Relationship between polymorphism lle655Val and breast cancer risk studied



September 29th, 2005

The relationship between polymorphism lle655Val and breast cancer risk was studied by researchers at Harvard University.

"The erbB2 (HER2/neu) gene is found amplified in tumors. A single nucleotide polymorphism at codon 655 (lle655Val) has been studied in a number of case-control studies with respect to breast cancer risk, with conflicting results," scientists in the United States report.

D .G. Cox and colleagues stated, "The aim of the present study was to examine the association between this polymorphism and breast cancer risk in a prospective, predominantly Caucasian cohort of women, the Nurses' Health Study. We genotyped the lle655Val single...


Source: Women's Health Weekly (2005-09-29)

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