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Women's Health Weekly

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Breast Cancer



Catechol-O-methyltransferase polymorphism studied as predictor for breast cancer



October 6th, 2005

The catechol-O-methyltransferase polymorphism was studied by scientists in Japan as a predictor for breast cancer.

"Polymorphic catechol-O-methyltransferase (COMT) catalyzes the O-methylation of catechol estrogens. It has been reported that COMT polymorphism is a representative genetic trait related to the susceptibility of an individual to breast cancer," according to a report published in Oncology Reports.

"However, there is no consensus concerning the association between breast cancer in Japanese patients and COMT polymorphism," wrote H. Inoue and colleagues. "To analyze the polymorphism distribution in Japanese patients with breast cancer,...


Source: Women's Health Weekly (2005-10-06)

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