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Women's Health Weekly

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Breast Cancer



HMGA2 deemed unsuitable marker for detecting tumor cells in breast cancer



October 6th, 2005

Scientists revealed that HMGA2 is an unsuitable marker for detecting tumor cells in breast cancer.

"Previously, the human high mobility group protein member HMGA2 mRNA was reported to be expressed in peripheral blood of patients with breast cancer, but not in healthy individuals. Expression of HMGA2 in blood was suggested to be an independent indicator of poor prognosis in metastatic breast cancer," researchers in Austria reported.

"These very promising findings propose HMGA2 as a potential marker for the detection of circulating tumor cells in peripheral blood. Therefore, we analyzed peripheral blood specimens from healthy controls and patients with...


Source: Women's Health Weekly (2005-10-06)

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