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Women's Health Weekly

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Breast Cancer



Cisplatin-epirubicin-paclitaxel used to treat operable breast cancer



October 13th, 2005

Scientists evaluated a 2-month cisplatin-epirubicin-paclitaxel (PET) weekly combination as primary systemic therapy for large operable breast cancer.

"The present study aimed to define the antitumor activity of 8 PET weekly cycles with granulocyte colony-stimulating factor (G-CSF) support in patients with large operable breast cancer. Operable breast cancer (T2-3 N0-1; T>3 cm) patients received 8 preoperative weekly cycles of cisplatin 30 mg/m2, epirubicin 50 mg/m2 and paclitaxel 120 mg/m2, with G-CSF (5 mcg/kg, days 3-5) support. Sixty-three patients (T2/T3=30/33; N0/N+=8/55) were enrolled," scientists writing in the journal...


Source: Women's Health Weekly (2005-10-13)

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