Women's Health Weekly
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Cancer Risk Factors
EMSY gene evaluated for association in breast and ovarian cancer risk
October 13th, 2005
The EMSY gene was evaluated for its possible association in breast and ovarian cancer risk in women. "EMSY could be involved in low-level susceptibility to breast and ovarian cancer," researchers in England report. "Gene amplification is seen in a proportion of breast and ovarian tumors and correlates with poor prognosis in breast cancer patients. Furthermore," stated P. R. Benusiglio and colleagues, "the EMSY protein silences a transcription activation domain in BRCA2 exon 3. We used a genetic association study design to determine if common genetic variation (frequency=5%) in EMSY was associated with breast or ovarian cancer risk in the British...
Source: Women's Health Weekly (2005-10-13)
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