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Breast Cancer

Scientists examine gene variants that may be associated with breast cancer risk

"Common polymorphisms in genes that affect estrogen levels may be associated with breast cancer risk," researchers in the United States report. "They investigated the associations between breast cancer and sequence variants in several genes in the estradiol/estrone metabolism pathway (CYP1A1*2A, CYP1A2*1F, CYP1B1Leu⁴³²Val, CYP3A4*1B, COMT Val¹⁵⁸Met, SULT1A1Arg²¹³His) as well as the Arg⁵⁵⁴Lys variant in AHR (a transcription factor for CYP1A1, CYP1A2, and CYP1B1) in a...

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