Women's Health Weekly
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Breast Cancer Risk Factors
Variants in BRCA1 gene evaluated for breast cancer risk
October 13th, 2005
Variants in the BRCA1 gene were evaluated for their effect on breast cancer risk. "Rare, highly penetrant germ line mutations in BRCA1 strongly predispose women to a familial form of breast and ovarian cancer," scientists in the United States report. "Whether common variants (either coding or noncoding) at this locus contribute to the more common form of the disease is not yet known." M. L. Freedman and colleagues "tested common variation across the BRCA1 locus in African American, Native Hawaiian, Japanese, Latino, and White women in the Multiethnic Cohort Study. Specifically, 28 single nucleotide polymorphisms (SNPs) spanning...
Source: Women's Health Weekly (2005-10-13)
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