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Women's Health Weekly

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Cervical Cancer



Role of polymorphisms of tumor necrosis factor in cervical cancer examined



October 13th, 2005

The role of polymorphisms of tumor necrosis factor in cervical cancer was recently examined.

According to a study from Brazil, "Infection with oncogenic human papillomavirus (HPV) is considered to be the major risk factor for cervical cancer. Tumor necrosis factor (TNF) is a pluripotent cytokine that plays an important role in inhibiting the action of microbial agents, and TNF microsatellite polymorphisms have been associated with several diseases, including cancer and viral infections."

The study by R. T. Simoes and colleagues "analyzed the associations between TNFa to -e microsatellite polymorphisms and the severity of squamous...


Source: Women's Health Weekly (2005-10-13)

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