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Women's Health Weekly

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Breast Cancer



SELDI-TOF-MS developed to detect biomarkers for early diagnosis of breast cancer



October 20th, 2005

SELDI-TOF-MS was developed to detect biomarkers for the early diagnosis of breast cancer.

"Breast cancer has never had any good serum tumor markers. Therefore, we developed and evaluated a proteomics approach to searching for new biomarkers and building diagnostic models," scientists in People's Republic Of China report.

"SELDI-TOF-MS ProteinChip was used to detect the serum protein patterns of 49 breast cancer patients, 51 patients with benign breast diseases, and 33 healthy women," wrote Y. Hu and colleagues, Zhejiang University. "The diagnostic models were developed and validated using bioinformatics tools such as artificial neural networks and...


Source: Women's Health Weekly (2005-10-20)

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