Women's Health Weekly
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Breast Cancer Vaccine Development
Trichorhinophalangeal syndrome gene overexpressed in breast cancer
October 20th, 2005
The gene associated with trichorhinophalangeal syndrome in humans is overexpressed in breast cancer. According to a study from Canada, Australia, and the United States, "A comprehensive differential gene expression screen on a panel of 54 breast tumors and >200 normal tissue samples using DNA microarrays revealed 15 genes specifically overexpressed in breast cancer. One of the most prevalent genes found was trichorhinophalangeal syndrome type 1 (TRPS-1), a gene previously shown to be associated with three rare autosomal dominant genetic disorders known as the trichorhinophalangeal syndromes." "A number of corroborating methodologies, including in...
Source: Women's Health Weekly (2005-10-20)
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