Cervical Cancer
Examination E7 indicates pRb as important target in cervical cancer analysis
Published in Women's Health Weekly, October 20th, 2005
According to a study from the United States, "High-risk human papillomaviruses encode two oncogenes, E6 and E7, expressed in nearly all cervical cancers. Although E7 protein is best known for its ability to inactivate the retinoblastoma tumor suppressor protein, pRb, many other activities for E7 have been proposed in in vitro studies."
"Herein," proposed S. Balsitis and colleagues, University of Wisconsin, "we describe studies that allowed us to define unambiguously the pRb-dependent and -independent activities of E7 for the first time in vivo. In...
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