Women's Health Weekly
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Anorexia Nervosa
Multiple DRD2 polymorphisms associated with anorexia nervosa
October 20th, 2005
Multiple DRD2 polymorphisms are associated with anorexia nervosa. According to a study from the United States, "To investigate whether the dopaminergic system plays a role in the etiology of anorexia nervosa (AN) via the dopamine D2 receptor, we investigated association and transmission disequilibrium at seven single-nucleotide polymorphisms (SNPs) spanning about 75 kbp of the gene DRD2. We studied 191 probands with a DSM-IV diagnosis of AN, 457 parents and affected relatives with a DSM-IV eating disorder diagnosis, and 98 unrelated, female, normal weight controls." "The -141 C/- insertion/deletion (-141 Indel), previously shown to affect DRD2...
Source: Women's Health Weekly (2005-10-20)
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