Women's Health Weekly
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Aromatase Inhibitors
Effects of aromatase inhibitors on vascular system examined
October 20th, 2005
The effects of aromatase inhibitors on the vascular system were recently examined. "Aromatase inhibitors (AIs) are becoming the endocrine treatment of first choice for postmenopausal women with hormone receptor-positive breast cancer and are under investigation for use in breast cancer prevention. AIs reduce circulating estrogen to barely detectable concentrations," scientists in England report. Howell and Cuzick wrote, "It is possible that such a low concentration will be deleterious to the vascular system since estrogen receptors are known to be in the cell walls of blood vessels and estrogen is thought to be important in maintaining blood vessel...
Source: Women's Health Weekly (2005-10-20)
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