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Women's Health Weekly

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Eclampsia



Role for large trinucleotide repeat expansion in pre-eclampsia not supported



October 27th, 2005

The role for a large trinucleotide repeat expansion in pre-eclampsia was not supported by findings in a recent study; however, the association of a gene mutation was not ruled out.

According to recent research from Australia, "Pre-eclampsia/eclampsia is a serious disorder of human pregnancy that has a worldwide incidence of 2-10% and carries a severe morbidity and mortality risk for both mother and child. Its precise cause remains unknown."

"However, there is increasing evidence of an underlying complex maternal genetic susceptibility," wrote K. A. Freed and colleagues. "Its high population incidence in the face of strong negative selection pressure...


Source: Women's Health Weekly (2005-10-27)

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