Women's Health Weekly
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Women's Health Weekly
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Antiproliferative Agents
CSAB suppresses proliferation of neoplastic human HeLa cells
October 27th, 2005
CSAB suppresses the proliferation of neoplastic human HeLa cells. "A series of twenty alkyl-, halo-, and methoxy-aryl-substituted 2-[(carboxymethyl)sulfanyl]-4-oxo-4-arylbutanoic acids were synthesized. The new compounds, called CSAB, suppressed proliferation of human cervix carcinoma, HeLa cells, in vitro in a concentration range of .644 to 29.48 mcM/L," investigators in Serbia Montenegro reported. "Two compounds exhibit antiproliferative activity in sub-micromolar concentrations (16, 19). Five compounds act in low micromolar concentrations (<2 mcM/L). The most active compounds exert lower cytotoxicity toward healthy human peripheral blood...
Source: Women's Health Weekly (2005-10-27)
|
