Oncology

Stat3 is an upstream regulator of cancer stimulating proteins in breast tumors

Published in Women's Health Weekly, October 27th, 2005

Stat3 (signal transducer and activator of transcription 3) is an upstream regulator of cancer stimulating proteins in breast tumors.

According to a study from the United States, "the constitutive activation of Stat3 is frequently detected in breast cancer tissues and cell lines. Stat3 has been classified as a proto-oncogene, because an activated form of Stat3 can mediate oncogenic transformation in cultured cells and tumor formation in nude mice."

"Since Stat3 may play an important role in breast cancer, it is of interest to investigate the expression of phosphorylated Stat3, an activated form of Stat3, and its downstream mediators specifically in...

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Source: Women's Health Weekly (2005-10-27)

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