Women's Health Weekly
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Biomarkers
Estrogen-responsive finger protein proposed as potential biomarker for breast cancer
November 3rd, 2005
Estrogen-responsive finger protein (Efp) was proposed as a new potential biomarker for breast cancer. "Efp is a member of RING finger-B box-Coiled Coil family and is also a downstream target of estrogen receptor alpha. Previously, Efp was shown to mediate estrogen-induced cell growth, which suggests possible involvement in the development of human breast carcinomas. In this study, we examined expression of Efp in breast carcinoma tissues and correlated these findings with various clinicopathologic variables," researchers in Japan reported. "Thirty frozen specimens of breast carcinomas were used for immunohistochemistry and laser capture...
Source: Women's Health Weekly (2005-11-03)
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