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Women's Health Weekly

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Breast Cancer



Further studies are needed to address the role of estrogen receptor beta in breast cancer



November 3rd, 2005

A multicenter investigation aimed at reaching a consensus on the immunohistochemical detection of estrogen receptor (ER) beta in archival formalin-fixed paraffin embedded human breast tissue determined that further studies are needed.

According to a study from England, "ER alpha is a well-established independent prognostic factor in breast cancer whose presence determines the clinical implications of adjuvant endocrine therapy. A second receptor, ER beta has been described, and a number of studies have examined its expression in breast tissue."

"However elucidation of the role played by ER beta has been hampered by published immunohistochemical...


Source: Women's Health Weekly (2005-11-03)

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