Breast Cancer
Nonmammary apomucins show a potential role in breast cancer glycoimmunology
Published in Women's Health Weekly, November 3rd, 2005
According to a study from Uruguay, "An incomplete elongation of O-glycan saccharide chains in mucins have been found in epithelial cancers, leading to the expression of shorter carbohydrate structures, such as the Tn antigen (GalNAc-O-Ser/Thr). This antigen is one of the most specific human cancer-associated structures and is capable of inducing effective immune responses against cancer cells."
T. Freire and associates reported in a recent issue of Cancer Research, "We aimed to investigate the causes of the expression of Tn antigen in the Tn-rich MCF-7 breast cancer...
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