Women's Health Weekly
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Breast Cancer Vaccine
Antibody 5C3 recognizes heteropolymer of cytokeratin 9
November 3rd, 2005
Scientists have characterized the reactive antigen of monoclonal antibody 5C3 raised against invasive breast tumor tissue in a recent issue of the Journal of Immunological Methods. According to recent research from Ireland, "Monoclonal antibodies (MAbs) provide a powerful tool for the identification of novel tumor associated antigens. In an attempt to identify such an antigen, MAbs were generated by immunization with paraffin wax-embedded formalin-fixed invasive ductal breast tumor tissue from a patient who relapsed following an initial response to adjuvant chemotherapy." "Extensive immunocytochemical and Western blot analysis of a range of...
Source: Women's Health Weekly (2005-11-03)
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