Women's Health Weekly
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Chemotherapy
Tamoxifen did not affect serum IL-6, urinary HS and GAG levels
November 3rd, 2005
Tamoxifen (TAM) did not significantly affect serum interleukin-6 (IL-6), urinary heparan sulphate (HS), and glycosaminoglycans (GAGs) levels after 6 months. According to recent research from Turkey, "Leukocyte arylsulphatase A (AS-A) was shown to be significantly high in newly-diagnosed breast cancer patients. Previous reports imply a connection between serum IL-6 and breast cancer, possibly through a modulation of enzymes involved in estrogen synthesis." "Abnormal distribution of heparan sulphate proteoglycans (HSPGs) in malignant breast epithelial cells suggests that they play a key role in the regulation of cell growth. Estradiol is believed to be...
Source: Women's Health Weekly (2005-11-03)
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