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Women's Health Weekly

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Breast Cancer



Genetic aberrations may be possible molecular fingerprint of radiation-associated breast cancer



November 10th, 2005

Genetic aberrations identified from a nuclear fallout area and from Western New York may be a possible molecular fingerprint of radiation-associated breast cancer.

Scientists in the United States reported, "High-resolution array comparative genomic hybridisation (aCGH) analysis of DNA copy number aberrations (CNAs) was performed on breast carcinomas in premenopausal women from Western New York (WNY) and from Gomel, Belarus, an area exposed to fallout from the 1986 Chernobyl nuclear accident. Genomic DNA was isolated from 47 frozen tumor specimens from 42 patients and hybridised to arrays spotted with more than 3000 BAC clones."

"In all, 20 samples...


Source: Women's Health Weekly (2005-11-10)

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