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Women's Health Weekly

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Cancer Therapy



Bendamustine prolongs progression-free survival in metastatic breast cancer



November 10th, 2005

Researchers claim that bendamustine prolongs progression-free survival in metastatic breast cancer (MBC).

"Two i.v. regimens, bendamustine, methotrexate and 5-fluorouracil (BMF) and cyclophosphamide, methotrexate and 5-fluorouracil (CMF) were compared as first-line therapy in a randomized, open, multicenter phase III trial including 364 patients with MBC. Bendamustine is an anti-neoplastic agent with alkylating, but also additional, so far unclear, mechanisms of action," scientists writing in the journal Anti-Cancer Drugs reported.

"We wanted to show the superiority of BMF over CMF in terms of time to progression (TTP) (primary endpoint),...


Source: Women's Health Weekly (2005-11-10)

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