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Labor & Delivery

Acceptable level of maternal and neonate side effects found with patient-controlled analgesia

Published in Women's Health Weekly, November 10th, 2005

An acceptable level of maternal and neonate side effects was found with remifentanil patient-controlled analgesia.

"Remifentanil has been suggested as an ideal opioid for patient-controlled analgesia (PCA) in labor, but the safety profile has not been established. The aims of a preliminary prospective observational study" by scientists in England "were to investigate the maternal side-effects and early neonatal effects, and to assess the placental transfer of remifentanil PCA during labor."

"Women with no known obstetric complications or contraindication to remifentanil were recruited (n=50)," wrote I. Volikas and colleagues. "Remifentanil was...

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