Women's Health Weekly
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Breast Cancer
HER-2/neu amplifications status by FISH can be accurately and reliably evaluated
November 17th, 2005
HER-2/neu amplifications status by fluorescence in situ hybridization (FISH) can be accurately and reliably evaluated in archival specimens. Researchers in the United States conducted a study "to assess the usefulness of FISH for HER-2/neu amplification of breast carcinoma in archival fine needle aspiration biopsy (FNAB) specimens. All FISH performed on formalin-fixed, paraffin-embedded surgical specimens during January 2003-August 2003 at the University of California, Irvine Medical Center were selected. Prior FNABs were retrieved." "One cytologic slide was destained in each case. The results were compared with those obtained on histologic paired t...
Source: Women's Health Weekly (2005-11-17)
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