Women's Health Weekly
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Breast Cancer
Low-density microarrays suitable for characterization of tumor cell lines
November 17th, 2005
Low-density microarrays are suitable for the molecular characterization of breast tumor cell lines. In a recent study, oncologists in Belgium "designed a low-density microarray carrying 132 DNA capture sequences highly specific for genes known to be differentially expressed among breast tumors and BCC lines or associated with specific tumor properties (cell cycle alteration, proteolysis, adhesion, hormone sensitivity, etc)." "We analyzed gene expression in 11 BCC lines among which 6 had already been extensively studied (BT-474, Hs578T, MCF-7, MDA-MB-231, MDA-MB-453, T-47D) and 5 were still poorly characterized (Evsa-T, IBEP-1, IBEP-2, IBEP-3,...
Source: Women's Health Weekly (2005-11-17)
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