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Women's Health Weekly

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Breast Cancer Therapy



New aromatase inhibitors for treatment of metastatic breast cancer examined



November 17th, 2005

Researchers examine new aromatase inhibitors as second-line endocrine therapy in postmenopausal patients with metastatic breast carcinoma in a recent issue of the journal Cancer.

According to a study from Italy, "New aromatase inhibitors (AI) (second-generation: formestane and fadrozole; third-generation: letrozole, anastrozole, vorozole, and exemestane) have been tested in several controlled clinical trials after tamoxifen failure in metastatic breast carcinoma (MBC). They have resulted in better survival compared with megestrol acetate (MEG) in a number of studies."

"The authors performed a pooled analysis including all the Phase III trials...


Source: Women's Health Weekly (2005-11-17)

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