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Women's Health Weekly

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DNA Damage



Endogenous DNA damage detected among individuals with cancer



November 17th, 2005

Endogenous DNA damage was detected among individuals with cancer.

"Variation in the detection, signaling, and repair of DNA damage contributes to human cancer risk. To assess capacity to modulate endogenous DNA damage among radiologic technologists who had been diagnosed with breast cancer and another malignancy (breast-other, n=42), early-onset breast cancer (early-onset, age {{<=}}35; n=38), thyroid cancer (n=69), long-lived cancer-free individuals (hyper-normals, n=20) and cancer-free controls (n=49), we quantified DNA damage (single strand breaks and abasic sites) in untreated lymphoblastoid cell lines using the alkaline comet assay," scientists in the United...


Source: Women's Health Weekly (2005-11-17)

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