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Women's Health Weekly

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Breast Cancer



Studies advance knowledge in breast cancer research



November 17th, 2005

Breast cancer research advances have been reported from France, Brazil and the United States.

Study 1: Hypoxia-inducible factor-1 alpha overexpression predicts early breast cancer relapse.

"Hypoxia-inducible factor-1 alpha (HIF-1 alpha) is a transcription factor that is involved in tumor growth and metastasis by regulating genes involved in response to hypoxia.

"HIF-1 alpha protein overexpression has been shown in a variety of human cancers, but only 2 studies have documented the prognostic relevance of HIF-1 alpha expression in breast cancer," researchers in France report.

"The aim of our study was to...


Source: Women's Health Weekly (2005-11-17)

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