Women's Health Weekly
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Osteoporosis
Indices of bone formation increase with teriparatide
November 17th, 2005
Although different mechanistically from alendronate, indices of bone formation increase with teriparatide. "An 18-month randomized double-blind study in postmenopausal women with osteoporosis was conducted" by scientists in France "to compare the effects of once-daily teriparatide 20 mcg with alendronate 10 mg on bone histomorphometry. Biopsies were obtained from 42 patients. Indices of bone formation were significantly higher after 6 to 18 months of teriparatide compared with alendronate treatment. Alendronate and teriparatide increased BMD, assessed by DXA, by different mechanisms of action, supported by changes in biochemical markers of bone turnover." ...
Source: Women's Health Weekly (2005-11-17)
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