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Women's Health Weekly

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Diagnostics



Radiation resistance in cervical cancer was associated with increased ICAM-3 expression



November 24th, 2005

Radiation resistance in cervical cancer was found to be associated with an increased expression of ICAM-3.

Researchers in South Korea conducted a study "to search for a marker that predicts the efficacy of radiation therapy in human cervical cancer, gene expression profiles between parental SiHa cervical cancer cells and radiation-resistant SiHa/R cells have been compared by the microarray technique. Microarray and Northern blot analyses demonstrated that the ICAM-3 expression was upregulated in SiHa/R cells."

Y.M. Chung and colleagues, Korea University determined, "This increased expression of ICAM-3 in SiHa cells enhanced cell survival by about...


Source: Women's Health Weekly (2005-11-24)

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