Women's Health Weekly
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Herpes Vaccine
Potential adult mouse model to study HSV-2 recurrence reported
November 24th, 2005
Researchers have observed recovery from and recurrence of HSV-2 infections in adult mice that were rescued from lethal vaginal infection by antiviral therapy. According to a study from the United States, "An adult mouse model for studies of latency and recurrence after vaginal HSV-2 infection is not available at present, largely because the infection kills most mice within 14 days. We describe here an antiviral therapy that rescues most vaginally infected mice from death. Vaginally infected mice were nearly all rescued by combined treatment with one dose of monoclonal anti-HSV glycoprotein D 3 days after infection plus valacyclovir in the drinking water on days 3, 4, 5,...
Source: Women's Health Weekly (2005-11-24)
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